Larissa can refer to:
Larissa (given name), female first name
Larissa (mythology), a nymph from Greek mythology
Saint Larissa, an early martyr venerated by the Roman Catholic and Russian Orthodox churches.
Larissa, an important city in Greece.
Larissa Prefecture, an administrative division of Greece, centered on the city of Larissa
AEL 1964, a football club from Larissa
Larissa, Hellenistic name of Shaizar, Syria (at the time settled by colonists from the Greek city)
Larissa, Turkey, an ancient city in Turkey, in the immediate vicinity of Menemen district of İzmir
Larissa (Argolis), the acropolis of Argos in Greece
Larissa (moon), a moon of Neptune
1162 Larissa, an asteroid
Larisa (film), a 1980 short film directed by Elem Klimov
(de la Irina de ziua mea)